Tizanidine, sold under the brand names Zanaflex and Sirdalud among others, is an α 2 -adrenergic receptor agonist and muscle relaxant which is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [1][3][4] Its effectiveness appears to be similar to that of other muscle relaxants like. Tizanidine (Zanaflex) is a prescription muscle relaxant that is not a controlled substance. Physical dependence can develop, and suddenly stopping treatment may cause withdrawal symptoms, including high blood pressure and a fast heart rate. Zanaflex (Tizanidine) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Tizanidine (Zanaflex) is a muscle relaxant that treats muscle spasms. It relaxes your muscles, which reduces muscle stiffness. Medscape - Spasticity-specific dosing for Zanaflex (tizanidine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost. Learn about Zanaflex: What is it used for, what you need to know before taking, important warnings and safety info, how to take, side effects and more. Find patient medical information for Tizanidine (Zanaflex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Zanaflex is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Zanaflex is used to treat spasticity in adults, such as that associated with diseases like multiple sclerosis and spinal cord injuries, by temporarily relaxing muscle tone. Zanaflex is a central alpha-2-adrenergic agonist indicated for the management of spasticity. Because of the short duration of therapeutic effect, treatment with Zanaflex should be reserved for. Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, including multiple sclerosis or certain injuries to the spine.